| Weight | 422.92 g/mol |
|---|---|
| Formula | C22H23ClN6O |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 8 |
losartan (114798-26-4)
Cozaar · Losartan Potassium · DuP 753
Score:
#92 in Biochemistry
,
#417 in Biology
,
#432 in Chemistry
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- Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy (The New England Journal of Medicine, 2001)
- Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol (The Lancet, 2002)
- Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trialthe Losartan Heart Failure Survival Study ELITE II (The Lancet, 2000)
- Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE) (The Lancet, 1997)
- Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol (The Lancet, 2002)
- Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome (Science, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Cozaar
- Losartan Potassium
- DuP 753
- DuP-753
- DuP753
- MK-954
- MK 954
- MK954
- 2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol
- Losartan Monopotassium Salt
-
SMILESCCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl
-
InChIKeyPSIFNNKUMBGKDQ-UHFFFAOYSA-N
- Pubchem - losartan
- Wikipedia - losartan
Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure. Other uses include for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth.
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Estimated Properties
| Boiling Point | 500.73 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.44 g/cm3 | EPA T.E.S.T. |
| Flash Point | 329.64 C | EPA T.E.S.T. |
| Water Solubility | 2.51 mg/L | EPA T.E.S.T. |
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