| Weight | 411.373 g/mol |
|---|---|
| Formula | C21H28Cl2N2O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 8 |
Hydroxyzine hydrochloride (14729-22-7, 1244-76-4)
Hydroxyzine · Vistaril · Atarax
Score:
#729 in Neuroscience
,
#3212 in Biology
,
#4018 in Chemistry
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- A pilot clinical trial of oral pentosan polysulfate and oral hydroxyzine in patients with interstitial cystitis (The Journal of Urology, 2003)
- Hydroxyzine therapy for interstitial cystitis (Urology, 1998)
- Molecularly imprinted polymer based potentiometric sensor for the determination of hydroxyzine in tablets and biological fluids (Analytica Chimica Acta, 2008)
- Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study. (The Journal of Clinical Psychiatry, 2002)
- Prospective Controlled Study of Hydroxyzine and Cetirizine in Pregnancy (Annals of Allergy Asthma & Immunology, 1997)
- The relative antihistaminic and psychomotor effects of hydroxyzine and cetirizine (Clinical Pharmacology & Therapeutics, 1987)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Hydroxyzine
- Vistaril
- Atarax
- Hydroxyzine Pamoate
- Durrax
- 2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol
- Orgatrax
- Hydroxyzine Dihydrochloride
-
SMILESC1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl
-
InChIKeyIPSVAUIEEPSJRZ-UHFFFAOYSA-N
- Pubchem - Hydroxyzine hydrochloride
- Wikipedia - hydroxyzine hydrochloride
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is a first-generation antihistamine. It was first synthesized by Union Chimique Belge in 1956 and was marketed by Pfizer in the United States later the same year and is still widely used today. Because of its antihistamine effects, it can be used for the treatment of severe cases of itching, hyperalgesia, and motion sickness-induced nausea; it has also been used in some cases to relieve the effects of opioid withdrawal.
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