Weight | 246.306 g/mol |
---|---|
Formula | C15H18O3 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 4 |
Loxoprofen (80382-23-6, 68767-14-6)
loxoprofen sodium dihydrate · loxoprofen sodium, (R*,S*)-isomer · CS-600
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- Methotrexate-Loxoprofen Interaction : Involvement of Human Organic Anion Transporters hOAT1 and hOAT3 (Drug Metabolism and Pharmacokinetics, 2004)
- Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-Na, an anti-inflammatory prodrug (Biochemical Pharmacology, 1991)
- Effectiveness of a nonsteroidal anti-inflammatory drug for nocturia on patients with benign prostatic hyperplasia: a prospective non-randomized study of loxoprofen sodium 60 mg once daily before sleeping. (Acta Medica Okayama, 2004)
- Optical Inversion of (2R)-to (2S)-Isomers of 2-[4-(2-Oxocyclopentylmethyl)-phenyl] propionic Acid (Loxoprofen), a New Anti-inflammatory Agent, and Its Monohydroxy Metabolites in the Rat (Chemical & Pharmaceutical Bulletin, 1984)
- Application of antibody-mediated extraction for the stereoselective determination of the active metabolite of loxoprofen in human and rat plasma (Chirality, 1992)
- Column liquid chromatography for the simultaneous determination of the enantiomers of loxoprofen sodium and its metabolites in human urine (Journal of Chromatography B: Biomedical Sciences and Applications, 1985)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - loxoprofen sodium dihydrate
- loxoprofen sodium, (R*,S*)-isomer
- CS-600
- sodium loxoprofen
- 2-(4-((2-oxocyclopentyl)methyl)phenyl)propionic acid
- 2-OCPPP
- 156-S
- CS 600
- loxoprofen alcohol
- sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate
-
SMILESCC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O
-
InChIKeyYMBXTVYHTMGZDW-UHFFFAOYSA-N
- Pubchem - Loxoprofen
- Wikipedia - loxoprofen
Loxoprofen (INN) is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. It is marketed in Brazil, Mexico and Japan by Sankyo as its sodium salt, loxoprofen sodium, under the trade name Loxonin, in Argentina as Oxeno, in India as Loxomac, and in Thailand as Japrolox. It is available in these countries for oral administration, and a transdermal preparation was approved for sale in Japan on January 2006.
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