| Weight | 302.37 g/mol |
|---|---|
| Formula | C18H22O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Masoprocol (500-38-9, 27686-84-6)
Nordihydroguaiaretic Acid · Actinex · meso-Nordihydroguaiaretic Acid
Score:
#1257 in Biochemistry
,
#3107 in Biology
,
#3884 in Chemistry
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- Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets. (Prostaglandins, Leukotrienes and Medicine, 1984)
- Nordihydroguaiaretic acid protects hippocampal neurons against amyloid -peptide toxicity, and attenuates free radical and calcium accumulation (Brain Research, 1994)
- A double-blind, vehicle-controlled study evaluating masoprocol cream in the treatment of actinic keratoses on the head and neck (Journal of The American Academy of Dermatology, 1991)
- Nordihydroguaiaretic acid blocks the synaptic component of long-term potentiation and the associated increases in release of glutamate and arachidonate: An in vivo study in the dentate gyrus of the rat (Neuroscience, 1989)
- Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice (Aging Cell, 2008)
- Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid (Journal of Ethnopharmacology, 2005)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Nordihydroguaiaretic Acid
- Actinex
- meso-Nordihydroguaiaretic Acid
- Nordihydroguaiaretic Acid, (R*,S*)-Isomer
- (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
- meso Nordihydroguaiaretic Acid
- Dihydronorguaiaretic Acid
-
SMILESCC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
-
InChIKeyHCZKYJDFEPMADG-UHFFFAOYSA-N
- Pubchem - Masoprocol
- Wikipedia - masoprocol
Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer. Also called nordihydroguaiaretic acid, NDGA, and actinex.
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