| Weight | 325.434 g/mol |
|---|---|
| Formula | C15H23N3O3S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
Mecillinam (32887-01-7)
Amdinocillin · Penicillin Hx · FL-1060
Score:
#395 in Microbiology
,
#3106 in Biology
,
#3883 in Chemistry
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- Environmental risk assessment of antibiotics: comparison of mecillinam, trimethoprim and ciprofloxacin (Journal of Antimicrobial Chemotherapy, 2000)
- Mutant isolation and molecular cloning of mre genes, which determine cell shape, sensitivity to mecillinam, and amount of penicillin-binding proteins in Escherichia coli. (Journal of Bacteriology, 1987)
- A Canadian National Surveillance Study of Urinary Tract Isolates from Outpatients: Comparison of the Activities of Trimethoprim-Sulfamethoxazole, Ampicillin, Mecillinam, Nitrofurantoin, and Ciprofloxacin (Antimicrobial Agents and Chemotherapy, 2000)
- The mechanism of action of mecillinam (Journal of Antimicrobial Chemotherapy, 1977)
- Cluster of mrdA and mrdB genes responsible for the rod shape and mecillinam sensitivity of Escherichia coli. (Journal of Bacteriology, 1980)
- Mecillinam (FL 1060), a 6-Amidinopenicillanic Acid Derivative: Bactericidal Action and Synergy In Vitro (Antimicrobial Agents and Chemotherapy, 1975)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Amdinocillin
- Penicillin Hx
- FL-1060
- FL 1060
- FL1060
-
SMILESCC1(C(N2C(S1)C(C2=O)N=CN3CCCCCC3)C(=O)O)C
-
InChIKeyBWWVAEOLVKTZFQ-UHFFFAOYSA-N
- Pubchem - Mecillinam
- Wikipedia - Amdinocillin
Mecillinam (INN) or amdinocillin (USAN) is an extended-spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. It is used primarily in the treatment of urinary tract infections, and has also been used to treat typhoid and paratyphoid fever. Because mecillinam has very low oral bioavailability, an orally active prodrug was developed: pivmecillinam.
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Mecillinam
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