| Weight | 218.253 g/mol |
|---|---|
| Formula | C9H18N2O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 6 |
meprobamate (57-53-4)
Miltown · Equanil · Meprospan
Score:
#143 in Neuroscience
,
#693 in Biology
,
#747 in Chemistry
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- The effects of meprobamate, barbiturates, d-amphetamine and promazine on experimentally induced conflict in the rat (Psychopharmacology, 1960)
- Increase of ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration in man and in rats (The American Journal of Medicine, 1971)
- Barbiturates and meprobamate: Decreases in catecholamine turnover of central dopamine and noradrenaline neuronal systems and the influence of immobilization stress (Brain Research, 1972)
- THE PHARMACOLOGICAL PROPERTIES OF 2-METHYL-2-n-PROPYL-1,3-PROPANEDIOL DICARBAMATE (MILTOWN), A NEW INTERNEURONAL BLOCKING AGENT (Journal of Pharmacology and Experimental Therapeutics, 1954)
- Effects of Prenatal Meprobamate and Chlordiazepoxide Hydrochloride on Human Embryonic and Fetal Development (The New England Journal of Medicine, 1974)
- EFFECTS OF CHLORPROMAZINE, MEPROBAMATE, PENTOBARBITAL AND MORPHINE ON SELF-STIMULATION (Journal of Pharmacology and Experimental Therapeutics, 1960)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Miltown
- Equanil
- Meprospan
- Visano
- Tranmep
- Mprobamate Richard
- Dapaz
-
SMILESCCCC(C)(COC(=O)N)COC(=O)N
-
InChIKeyNPPQSCRMBWNHMW-UHFFFAOYSA-N
- Pubchem - meprobamate
- Wikipedia - meprobamate
Meprobamate marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines due to their wider therapeutic index (lower risk of toxicity at therapeutically prescribed doses) and lower incidence of serious side effects.
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Estimated Properties
| Boiling Point | 294.07 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.15 g/cm3 | EPA T.E.S.T. |
| Flash Point | 197.85 C | EPA T.E.S.T. |
| Water Solubility | 3541.61 mg/L | EPA T.E.S.T. |
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meprobamate
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