Weight | 284.399 g/mol |
---|---|
Formula | C19H24O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
Methyltrienolone (965-93-5)
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- Androgen Receptor Assay with [3H]Methyltrienolone (R1881) in the Presence of Progesterone Receptors* (Endocrinology, 1979)
- Methyltrienolone, a specific ligand for cellular androgen receptors (Steroids, 1975)
- Assay of androgen binding sites by exchange with methyltrienolone (R 1881) (Steroids, 1976)
- Binding of [3H] methyltrienolone (R 1881) in rat prostate and human benign prostatic hypertrophy (BPH) (Steroids, 1976)
- Characterization of the Binding of a Potent Synthetic Androgen, Methyltrienolone, to Human Tissues (Journal of Clinical Investigation, 1978)
- Binding of methyltrienolone (R1881) to a progesterone receptor-like component of human prostatic cytosol. (Journal of Endocrinology, 1977)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1(CCC2C1(C=CC3=C4CCC(=O)C=C4CCC23)C)O
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InChIKeyCCCIJQPRIXGQOE-UHFFFAOYSA-N
- Pubchem - Methyltrienolone
- Wikipedia - metribolone
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolicandrogenic steroid (AAS) and a 17-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR. It was investigated briefly for the treatment of advanced breast cancer in women in the late 1960s and early 1970s but was found to produce signs of severe hepatotoxicity at very low dosages, and its development was subsequently discontinued.
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