| Weight | 259.218 g/mol |
|---|---|
| Formula | C9H13N3O6 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
mizoribine (50924-49-7)
Score:
#1773 in Biochemistry
,
#3889 in Biology
,
#4899 in Chemistry
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- Mizoribine and mycophenolate mofetil. (Current Medicinal Chemistry, 1999)
- Guanine ribonucleotide depletion inhibits T cell activation : mechanism of action of the immunosuppressive drug mizoribine (Journal of Clinical Investigation, 1991)
- A multicenter trial of mizoribine compared with placebo in children with frequently relapsing nephrotic syndrome (Kidney International, 2000)
- Comparison of the effects of mizoribine with those of azathioprine, 6-mercaptopurine, and mycophenolic acid on T lymphocyte proliferation and purine ribonucleotide metabolism. (Molecular Pharmacology, 1992)
- Functional interaction of the immunosuppressant mizoribine with the 14-3-3 protein. (Biochemical and Biophysical Research Communications, 2000)
- Clinical pharmacokinetic study of mizoribine in renal transplantation patients. (Transplantation Proceedings, 1996)
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SMILESC1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N
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InChIKeyHZQDCMWJEBCWBR-UHFFFAOYSA-N
- Pubchem - mizoribine
- Wikipedia - mizoribine
Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo, Japan, in 1971. It is a natural product, first isolated from the mould Eupenicillium brefeldianum.
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mizoribine
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