| Weight | 287.406 g/mol |
|---|---|
| Formula | C21H21N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 5 |
Naftifine (65472-88-0)
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- Synthesis and structure-activity relationships of naftifine-related allylamine antimycotics (Journal of Medicinal Chemistry, 1986)
- In vitro activity of naftifine, a new antifungal agent. (Antimicrobial Agents and Chemotherapy, 1981)
- Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. (Antimicrobial Agents and Chemotherapy, 1984)
- Squalene and ergosterol biosynthesis in fungi treated with naftifine, a new antimycotic agent (Biochimica et Biophysica Acta, 1982)
- Naftifine. A review of its antimicrobial activity and therapeutic use in superficial dermatomycoses. (Drugs, 1991)
- In vivo antimycotic activity of naftifine. (Antimicrobial Agents and Chemotherapy, 1981)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN(CC=CC1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32
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InChIKeyOZGNYLLQHRPOBR-UHFFFAOYSA-N
- Pubchem - Naftifine
- Wikipedia - naftifine
Naftifine (brand name Exoderil) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (fungal infections). Naftifine has triple action: antifungal, antibacterial and anti-inflammatory. Its precise mechanism of action is unknown, but may involve selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.
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+
14489-75-9
(Chan-Lam coupling reaction)
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