| Weight | 254.289 g/mol |
|---|---|
| Formula | C15H14N2O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Nepafenac (78281-72-8)
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- Sigma-Aldrich - Nepafenac59.70 - 231.00 USD
- Fisher Scientific - Search for Nepafenac
- TCI - Nepafenac119.00 - 416.00 USD
- Topical Administration of Nepafenac Inhibits Diabetes-Induced Retinal Microvascular Disease and Underlying Abnormalities of Retinal Metabolism and Physiology (Diabetes, 2007)
- Nepafenac, a Unique Nonsteroidal Prodrug with Potential Utility in the Treatment of Trauma-Induced Ocular Inflammation: I. Assessment of Anti-Inflammatory Efficacy (Inflammation, 2000)
- Nepafenac, a Unique Nonsteroidal Prodrug with Potential Utility in the Treatment of Trauma-Induced Ocular Inflammation: II. In Vitro Bioactivation and Permeation of External Ocular Barriers (Inflammation, 2000)
- Topical nepafenac inhibits ocular neovascularization. (Investigative Ophthalmology & Visual Science, 2003)
- In vivo pharmacokinetics and in vitro pharmacodynamics of nepafenac, amfenac, ketorolac, and bromfenac (Journal of Cataract and Refractive Surgery, 2007)
- Inflammation-Mediated Retinal Edema in the Rabbit Is Inhibited by Topical Nepafenac (Inflammation, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC=C(C=C1)C(=O)C2=C(C(=CC=C2)CC(=O)N)N
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InChIKeyQEFAQIPZVLVERP-UHFFFAOYSA-N
- Pubchem - Nepafenac
- Wikipedia - nepafenac
Nepafenac (brand name Nevanac or Ilevro) is a nonsteroidal anti-inflammatory drug (NSAID), usually sold as a prescription eye drop 0.1% solution (Nevanac) or 0.3% solution (Ilevro). It is used to treat pain and inflammation associated with cataract surgery. Nepafenac is a prodrug of amfenac, an inhibitor of COX-1 and COX-2 activity.
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CHLOROBENZENE
(Grignard carbonyl)
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Nepafenac
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