| Weight | 302.37 g/mol |
|---|---|
| Formula | C18H22O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
NORDIHYDROGUAIARETIC ACID (500-38-9, 103185-28-0)
Masoprocol · Actinex · meso-Nordihydroguaiaretic Acid
Score:
#1286 in Biochemistry
,
#3155 in Biology
,
#3948 in Chemistry
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- Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets. (Prostaglandins, Leukotrienes and Medicine, 1984)
- Nordihydroguaiaretic acid protects hippocampal neurons against amyloid -peptide toxicity, and attenuates free radical and calcium accumulation (Brain Research, 1994)
- A double-blind, vehicle-controlled study evaluating masoprocol cream in the treatment of actinic keratoses on the head and neck (Journal of The American Academy of Dermatology, 1991)
- Nordihydroguaiaretic acid blocks the synaptic component of long-term potentiation and the associated increases in release of glutamate and arachidonate: An in vivo study in the dentate gyrus of the rat (Neuroscience, 1989)
- Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice (Aging Cell, 2008)
- Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid (Journal of Ethnopharmacology, 2005)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Masoprocol
- Actinex
- meso-Nordihydroguaiaretic Acid
- Nordihydroguaiaretic Acid, (R*,S*)-Isomer
- (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
- meso Nordihydroguaiaretic Acid
- Dihydronorguaiaretic Acid
-
SMILESCC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O
-
InChIKeyHCZKYJDFEPMADG-UHFFFAOYSA-N
- Pubchem - NORDIHYDROGUAIARETIC ACID
- Wikipedia - nordihydroguaiaretic acid
Nordihydroguaiaretic acid (NDGA) is an antioxidant compound found in the creosote bush (Larrea tridentata). The creosote plant has been used in herbal medicine, but its use is controversial. It was widely used during the 1950s as a food preservative and to preserve natural fibers, but was later banned after reports of toxicity during the early 1960s.
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