| Weight | 383.376 g/mol |
|---|---|
| Formula | C16H15F2N3O4S |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
pantoprazole (102625-70-7, 142678-35-1)
Protonix · pantoprazole sodium · BY 1023
Score:
#386 in Biochemistry
,
#1343 in Biology
,
#1564 in Chemistry
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- COMPARISON OF INHIBITORY EFFECTS OF THE PROTON PUMP-INHIBITING DRUGS OMEPRAZOLE, ESOMEPRAZOLE, LANSOPRAZOLE, PANTOPRAZOLE, AND RABEPRAZOLE ON HUMAN CYTOCHROME P450 ACTIVITIES (Drug Metabolism and Disposition, 2004)
- Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel (American Heart Journal, 2009)
- Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study (The American Journal of Gastroenterology, 2003)
- Pharmacokinetics, metabolism and interactions of acid pump inhibitors : Focus on omeprazole, lansoprazole and pantoprazole (Clinical Pharmacokinectics, 1996)
- Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose the PACA (Proton Pump Inhibitors And Clopidogrel Association) prospective randomized study. (Journal of the American College of Cardiology, 2009)
- Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison Studies (Clinical Pharmacology & Therapeutics, 2011)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Protonix
- pantoprazole sodium
- BY 1023
- SKF-96022
- BY-1023
- SK and F 96022
- SK and F-96022
-
SMILESCOC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC
-
InChIKeyIQPSEEYGBUAQFF-UHFFFAOYSA-N
- Pubchem - pantoprazole
- Wikipedia - pantoprazole
Pantoprazole, first sold under the brand name Protonix, is used for short-term treatment of erosive esophagitis associated with gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including ZollingerEllison syndrome. Some common side effects of pantoprazole use in adults include: headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and joint pain (>2%). Use of pantoprazole for a long period of time may lead to chronic inflammation of stomach lining or atrophic gastritis, vitamin B-12 deficiency, and low magnesium.
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