| Weight | 402.399 g/mol |
|---|---|
| Formula | C21H22O8 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
Nobiletin (478-01-3)
Score:
#878 in Neuroscience
,
#1747 in Biochemistry
,
#3854 in Biology
,
#4852 in Chemistry
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- Inhibitory Effect of Citrus Nobiletin on Phorbol Ester-induced Skin Inflammation, Oxidative Stress, and Tumor Promotion in Mice (Cancer Research, 2000)
- Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages (Biochemical Pharmacology, 2003)
- Inhibition of Activator Protein-1 Binding Activity and Phosphatidylinositol 3-Kinase Pathway by Nobiletin, a Polymethoxy Flavonoid, Results in Augmentation of Tissue Inhibitor of Metalloproteinases-1 Production and Suppression of Production of Matrix Metalloproteinases-1 and -9 in Human Fibrosarcoma HT-1080 Cells (Cancer Research, 2002)
- Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and A Pathology in a Transgenic Mouse Model of Alzheimer's Disease (Journal of Pharmacology and Experimental Therapeutics, 2008)
- A citrus flavonoid, nobiletin, suppresses production and gene expression of matrix metalloproteinase 9/gelatinase B in rabbit synovial fibroblasts. (The Journal of Rheumatology, 2000)
- Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells (Cancer Letters, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCOC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC
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InChIKeyMRIAQLRQZPPODS-UHFFFAOYSA-N
- Pubchem - Nobiletin
- Wikipedia - nobiletin
Nobiletin is a flavonoid isolated from citrus peels. It is an O-methylated flavone that has the activity to rescue bulbectomy-induced memory impairment.
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