| Weight | 378.433 g/mol |
|---|---|
| Formula | C17H26N6O4 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 12 |
Pentosidine (124505-87-9)
Score:
#1451 in Biochemistry
,
#3437 in Biology
,
#4290 in Chemistry
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- Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo. (Journal of Biological Chemistry, 1991)
- Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors. (Journal of Biological Chemistry, 1991)
- Pentosidine formation in skin correlates with severity of complications in individuals with long-standing IDDM (Diabetes, 1992)
- Chromatographic Quantitation of Plasma and Erythrocyte Pentosidine in Diabetic and Uremic Subjects (Diabetes, 1992)
- Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: renal implications in the pathophysiology of pentosidine. (Journal of The American Society of Nephrology, 1996)
- High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis (Proceedings of the National Academy of Sciences of the United States of America, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CN(C2=NC(=NC2=C1)NCCCC(C(=O)O)N)CCCCC(C(=O)O)N
-
InChIKeyAYEKKSTZQYEZPU-UHFFFAOYSA-N
- Pubchem - Pentosidine
- Wikipedia - pentosidine
Pentosidine is a biomarker for advanced glycation endproducts, or AGEs. It is a well characterized and easily detected member of this large class of compounds.
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