| Weight | 436.413 g/mol |
|---|---|
| Formula | C21H24O10 |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 7 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Phlorizin (7061-54-3, 60-81-1)
Phloridzin · Phlorhizin
Score:
#1714 in Biochemistry
,
#3809 in Biology
,
#4792 in Chemistry
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- Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. (Journal of Clinical Investigation, 1987)
- Phlorizin: a review. (Diabetes-metabolism Research and Reviews, 2005)
- Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase (FEBS Letters, 2000)
- Phlorizin as a competitive inhibitor of the active transport of sugars by hamster small intestine, in vitro (Biochimica et Biophysica Acta, 1962)
- Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter. (Biochemical Pharmacology, 2003)
- Complete primary structure of human and rabbit lactase-phlorizin hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme. (The EMBO Journal, 1988)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Phloridzin
- Phlorhizin
-
SMILESC1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O
-
InChIKeyIOUVKUPGCMBWBT-UHFFFAOYSA-N
- Pubchem - Phlorizin
- Wikipedia - phlorizin
Phlorizin (also referred to as phloridzin; chemical name phloretin-2'--D-glucopyranoside) is a glucoside of phloretin, a dihydrochalcone, a family of bicyclic flavonoids, which in turn is a subgroup in the diverse phenylpropanoid synthesis pathway in plants.
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Synthesis
Phlorin
+
Reactant
(Friedel-Crafts acylation)
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Phlorizin
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