| Weight | 461.511 g/mol |
|---|---|
| Formula | C24H31NO8 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 11 |
Orphenadrine citrate (4682-36-4)
Orphenadrine · Norflex · Disipal
Score:
#694 in Neuroscience
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#3093 in Biology
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#3864 in Chemistry
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- 5-HT2 antagonist ritanserin in neuroleptic-induced parkinsonism: a double-blind comparison with orphenadrine and placebo. (Clinical Neuropharmacology, 1990)
- Interactions of orphenadrine and phenobarbitone with chlorpromazine: plasma concentrations and effects in man. (British Journal of Clinical Pharmacology, 1975)
- Inhibition of oxidative drug metabolism by orphenadrine: in vitro and in vivo evidence for isozyme-specific complexation of cytochrome P-450 and inhibition kinetics. (Molecular Pharmacology, 1989)
- Orphenadrine and Methimazole Inhibit Multiple Cytochrome P450 Enzymes in Human Liver Microsomes (Drug Metabolism and Disposition, 1997)
- Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism. (Psychological Medicine, 1972)
- Difference between single and multiple dose pharmacokinetics of orphenadrine hydrochloride in man (European Journal of Clinical Pharmacology, 1982)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Orphenadrine
- Norflex
- Disipal
- Orphenadrine Hydrochloride
- Lysantin
- Methyldiphenylhydramine
- Mefenamine
- Mephenamine
- Sodium Mefenamine
- Norflex Orphenadrine Citrate
-
SMILESCC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
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- Pubchem - Orphenadrine citrate
- Wikipedia - orphenadrine citrate
Orphenadrine (sold under many brand names worldwide) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine. It is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs. It was discovered and developed in the 1940s.
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