| Weight | 391.421 g/mol |
|---|---|
| Formula | C16H29N3O8 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 7 |
DIETHYLCARBAMAZINE CITRATE (1642-54-2)
Diethylcarbamazine · Hetrazan · Carbamazine
Score:
#2497 in Biology
,
#3118 in Chemistry
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- Diethylcarbamazine-related antimicrobial activity in Mycobacterium tuberculosis-infected blood. (Antimicrobial Agents and Chemotherapy, 1998)
- Comparison of Ivermectin and Diethylcarbamazine in the Treatment of Onchocerciasis (The New England Journal of Medicine, 1985)
- Efficacy of single dose combinations of albendazole, ivermectin and diethylcarbamazine for the treatment of bancroftian filariasis (Transactions of The Royal Society of Tropical Medicine and Hygiene, 1998)
- Effect of yearly mass drug administration with diethylcarbamazine and albendazole on bancroftian filariasis in Egypt: a comprehensive assessment (The Lancet, 2006)
- Assessment of the efficacy of diethylcarbamazine on adult Wuchereria bancrofti in vivo (Transactions of The Royal Society of Tropical Medicine and Hygiene, 1997)
- Efficacy of Diethylcarbamazine in Eradicating Infection with Lymphatic-Dwelling Filariae in Humans (Clinical Infectious Diseases, 1985)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Diethylcarbamazine
- Hetrazan
- Carbamazine
- Notezine
- Diethylcarbamazine Monohydrochloride
- Aventis Brand of Diethylcarbamazine Citrate
- Loxuran
- Diethylcarbamazine Maleate
- Diethylcarbamazine Citrate (1:2)
- Diethylcarbamazine L-Tartrate (1:1)
- Diethylcarbamazine Citrate (1:1)
- Diethylcarbamazine Phosphate (1:1)
-
SMILESCCN(CC)C(=O)N1CCN(CC1)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
-
InChIKeyPGNKBEARDDELNB-UHFFFAOYSA-N
- Pubchem - DIETHYLCARBAMAZINE CITRATE
- Wikipedia - diethylcarbamazine citrate
Diethylcarbamazine (DEC) is a medication used in the treatment of filariasis including lymphatic filariasis, tropical pulmonary eosinophilia, and loiasis. It may also be used for prevention of loiasis in those at high risk. While it has been used for onchocerciasis (river blindness), invermectin is preferred.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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DIETHYLCARBAMAZINE CITRATE
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