| Weight | 427.417 g/mol |
|---|---|
| Formula | C20H21N5O6 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 9 |
Alimta (150399-23-8)
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- Front-line treatment of advanced non-small-cell lung cancer with MTA (LY231514, pemetrexed disodium, ALIMTA) and cisplatin : A multicenter phase II trial (Annals of Oncology, 2000)
- Pemetrexed (ALIMTA), a novel multitargeted antineoplastic agent. (Clinical Cancer Research, 2004)
- Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression (Biochemical Pharmacology, 2003)
- ALIMTA (pemetrexed disodium) as second-line treatment of non-small-cell lung cancer: a phase II study (Annals of Oncology, 2003)
- Phase II trial of pemetrexed disodium (ALIMTA, LY231514) in chemotherapy-nave patients with advanced non-small-cell lung cancer (Annals of Oncology, 2002)
- Phase II study of the multitargeted antifolate LY231514 (ALIMTA, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer (Annals of Oncology, 2000)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)O)C(=O)O
-
InChIKeyWBXPDJSOTKVWSJ-UHFFFAOYSA-N
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Synthesis
7355-55-7
+
Reactant
(Friedel-Crafts alkylation)
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