| Weight | 473.446 g/mol |
|---|---|
| Formula | C20H23N7O7 |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 7 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 10 |
10-Fthf (2800-34-2)
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SMILESC1C(NC2=C(N1)NC(=NC2=O)N)CN(C=O)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
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InChIKeyAUFGTPPARQZWDO-UHFFFAOYSA-N
- Pubchem - 10-Fthf
- Wikipedia - 10-Formyltetrahydrofolate
10-Formyltetrahydrofolate (10-CHO-THF) is a form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-CHO-THF is used as a substrate in formyltransferase reactions. This is important in purine biosynthesis, where 10-CHO-THF is a substrate for phosphoribosylaminoimidazolecarboxamide formyltransferase, as well as in the formylation of the methionyl initiator tRNA (fMet-tRNA), when 10-CHO-THF is a substrate for methionyl-tRNA formyltransferase.
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