| Weight | 496.569 g/mol |
|---|---|
| Formula | C21H36N8O6 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 11 |
Enterostatin (9001-78-9, 117830-79-2)
procolipase activation peptide · APGPR · Ala-Pro-Gly-Pro-Arg
Score:
#1922 in Biochemistry
,
#4089 in Biology
,
#5155 in Chemistry
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- Sigma-Aldrich - Search for Enterostatin
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- Enterostatin (Val-Pro-Asp-Pro-Arg), the activation peptide of procolipase, selectively reduces fat intake (Physiology & Behavior, 1991)
- Pancreatic procolipase propeptide, enterostatin, specifically inhibits fat intake (Physiology & Behavior, 1991)
- ENTEROSTATIN : A PEPTIDE REGULATING FAT INTAKE (Obesity Research, 1997)
- Differential inhibition of fat intake in two strains of rat by the peptide enterostatin. (American Journal of Physiology-regulatory Integrative and Comparative Physiology, 1992)
- The activation peptide of pancreatic procolipase decreases food intake in rats (Regulatory Peptides, 1988)
- Enterostatin suppresses food intake following injection into the third ventricle of rats (Brain Research, 1991)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - procolipase activation peptide
- APGPR
- Ala-Pro-Gly-Pro-Arg
- alanyl-prolyl-glycyl-prolyl-arginine
-
SMILESCC(C(=O)N1CCCC1C(=O)NCC(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)O)N
-
InChIKeyITZMJCSORYKOSI-UHFFFAOYSA-N
- Pubchem - Enterostatin
- Wikipedia - APGPR Enterostatin
Enterostatin is a pentapeptide derived from a proenzyme in the gastrointestinal tract called procolipase. It reduces food intake, in particular fat intake, when given peripherally or into the brain.
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Synthesis
L-Prolinamide, L-alanyl-
+
Reactant
(Alkylation of primary amines)
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