| Weight | 492.525 g/mol |
|---|---|
| Formula | C24H32N2O9 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 11 |
Enalapril maleate
Enalapril · MK 421 · Renitec
75847-73-3, 76095-16-4, 76420-75-2
Score:
#241 in Biochemistry
,
#928 in Biology
,
#1025 in Chemistry
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- TCI - Enalapril maleate50.00 - 173.00 USD
- Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators. (The New England Journal of Medicine, 1991)
- Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure (1991)
- Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) (American Journal of Cardiology, 1988)
- A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure (The New England Journal of Medicine, 1991)
- Angiotensin-neprilysin inhibition versus enalapril in heart failure. (The New England Journal of Medicine, 2014)
- The Effect of Nisoldipine as Compared with Enalapril on Cardiovascular Outcomes in Patients with Non-Insulin-Dependent Diabetes and Hypertension (The New England Journal of Medicine, 1998)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Enalapril
- MK 421
- Renitec
- MK-421
- MK421
- Renitek
-
SMILESCCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O.C(=CC(=O)O)C(=O)O
-
InChIKeyOYFJQPXVCSSHAI-UHFFFAOYSA-N
- Pubchem - Enalapril maleate
- Wikipedia - enalapril
Enalapril, sold under the brand name Vasotec among others, is a medication used to treat high blood pressure, diabetic kidney disease, and heart failure. For heart failure it is generally used with a diuretic such as furosemide. It is given by mouth or injection into a vein.
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Synthesis
Reactant
+
L-proline
(Schotten-Baumann amide from acid)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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Enalapril maleate
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