Weight | 474.985 g/mol |
---|---|
Formula | C25H31ClN2O5 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 9 |
QUINAPRIL HYDROCHLORIDE (82586-55-8)
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- Physical characteristics and chemical degradation of amorphous quinapril hydrochloride (Journal of Pharmaceutical Sciences, 2000)
- Effects of lyophilization on the physical characteristics and chemical stability of amorphous quinapril hydrochloride (Pharmaceutical Research, 2000)
- Effect of the pH grade of silicates on chemical stability of coground amorphous quinapril hydrochloride and its stabilization using pH-modifiers (Journal of Pharmaceutical Sciences, 2009)
- Solid-state surface acidity and pH-stability profiles of amorphous quinapril hydrochloride and silicate formulations (Journal of Pharmaceutical Sciences, 2010)
- Complex effects of drug/silicate ratio, solidstate equivalent pH, and moisture on chemical stability of amorphous quinapril hydrochloride coground with silicates (Journal of Pharmaceutical Sciences, 2011)
- Molecular and crystal structures of MDL27,467A hydrochloride and quinapril hydrochloride, two ester derivatives of potent angiotensin converting enzyme inhibitors. (Journal of Medicinal Chemistry, 1991)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O.Cl
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InChIKeyIBBLRJGOOANPTQ-UHFFFAOYSA-N
- Pubchem - QUINAPRIL HYDROCHLORIDE
- Wikipedia - quinapril hydrochloride
Quinapril (marketed under the brand name Accupril by Pfizer) is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure. A prodrug, it is converted to its active metabolite, quinaprilat, in the liver.
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Reactant
+
1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
(Schotten-Baumann amide from acid)
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