Weight | 459.97 g/mol |
---|---|
Formula | C25H30ClNO5 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 8 |
CLEMASTINE FUMARATE (14976-57-9, 15686-51-8)
Clemastine · Tavist · HS 592
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- Risk of developing life-threatening ventricular arrhythmia associated with terfenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine (American Journal of Cardiology, 1994)
- Evaluation ofin vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo (European Journal of Clinical Pharmacology, 1975)
- A comparison of triprolidine and clemastine on histamine antagonism and performance tests in man: Implications for the mechanism of drug induced drowsiness (European Journal of Clinical Pharmacology, 1975)
- Inhibition of idiosyncratic reactions to aspirin in asthmatic patients by clemastine. (Thorax, 1979)
- Randomized Controlled Trial of Clemastine Fumarate for Treatment of Experimental Rhinovirus Colds (Clinical Infectious Diseases, 1996)
- Effects of mizolastine and clemastine on actual driving and psychomotor performance in healthy volunteers (European Journal of Clinical Pharmacology, 1994)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Clemastine
- Tavist
- HS 592
- HS-592
- Meclastine
- 2-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine
- HS592
- Tavegyl
- Mecloprodin
-
SMILESCC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCCC3CCCN3C.C(=CC(=O)O)C(=O)O
-
InChIKeyPMGQWSIVQFOFOQ-UHFFFAOYSA-N
- Pubchem - CLEMASTINE FUMARATE
- Wikipedia - clemastine fumarate
Clemastine, also known as meclastin, is an antihistamine and anticholinergic. Unlike loratadine or fexofenadine, clemastine is a sedating antihistamine; however, it exhibits fewer other side effects than most of the widely used antihistamines. Clemastine is also classified as an antipruritic (i.e., it stops itching).
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