| Weight | 425.506 g/mol |
|---|---|
| Formula | C23H23NO5S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 2 |
KETOTIFEN FUMARATE (34580-14-8)
Ketotifen · Zaditen · Ketotiphen
Score:
#980 in Biochemistry
,
#2584 in Biology
,
#3224 in Chemistry
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- Sigma-Aldrich - KETOTIFEN FUMARATE42.90 - 187.50 USD
- Fisher Scientific - Search for KETOTIFEN FUMARATE
- TCI - KETOTIFEN FUMARATE102.00 - 354.00 USD
- The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome (Gut, 2010)
- The pharmacological properties of a new, orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene. (Drug Research, 1978)
- Terbutaline-induced desensitization of human lymphocyte beta 2-adrenoceptors. Accelerated restoration of beta-adrenoceptor responsiveness by prednisone and ketotifen. (Journal of Clinical Investigation, 1985)
- Prevention of asthma by ketotifen in infants with atopic dermatitis. (Annals of allergy, 1992)
- Prevention of Mast-Cell Degranulation by Ketotifen in Patients with Physical Urticarias (Annals of Internal Medicine, 1986)
- Benefit of ketotifen in patients with eosinophilic gastroenteritis (The American Journal of Medicine, 1991)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Ketotifen
- Zaditen
- Ketotiphen
- Ketotifene
- 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one
- Ketotiphene
-
SMILESCN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
-
InChIKeyYNQQEYBLVYAWNX-UHFFFAOYSA-N
- Pubchem - KETOTIFEN FUMARATE
- Wikipedia - ketotifen fumarate
Ketotifen, sold under the brand name Zaditor among others, is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis.
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