Weight | 366.844 g/mol |
---|---|
Formula | C22H19ClO3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 2 |
ATOVAQUONE (94015-53-9, 95233-18-4)
Score:
#114 in Microbiology
,
#1232 in Biology
,
#1416 in Chemistry
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- Clinical Studies of Atovaquone, Alone or in Combination with other Antimalarial Drugs, for Treatment of Acute Uncomplicated Malaria in Thailand (American Journal of Tropical Medicine and Hygiene, 1996)
- Atovaquone, a Broad Spectrum Antiparasitic Drug, Collapses Mitochondrial Membrane Potential in a Malarial Parasite (Journal of Biological Chemistry, 1997)
- Mutations in Plasmodium falciparum Cytochrome b That Are Associated with Atovaquone Resistance Are Located at a Putative Drug-Binding Site (Antimicrobial Agents and Chemotherapy, 2000)
- Resistance mutations reveal the atovaquonebinding domain of cytochrome b in malaria parasites (Molecular Microbiology, 1999)
- Atovaquone-Proguanil versus Mefloquine for Malaria Prophylaxis in Nonimmune Travelers: Results from a Randomized, Double-Blind Study (Clinical Infectious Diseases, 2001)
- Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS (The New England Journal of Medicine, 1993)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CC(CCC1C2=CC=C(C=C2)Cl)C3=C(C4=CC=CC=C4C(=O)C3=O)O
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InChIKeyBSJMWHQBCZFXBR-UHFFFAOYSA-N
- Pubchem - ATOVAQUONE
- Wikipedia - atovaquone
Atovaquone (alternative spelling: atavaquone) is a chemical compound that belongs to the class of naphthoquinones. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of ubiquinone, with antipneumocystic activity. It is manufactured in the US in the liquid form, or oral suspension, under the brand name Mepron.
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