| Weight | 445.903 g/mol |
|---|---|
| Formula | C22H24ClN3O5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
Loxapine succinate (27833-64-3)
Loxapine · Loxitane · Loxapine Hydrochloride
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- Tolerance phenomena with neuroleptics catalepsy, apomorphine stereotypies and striatal dopamine metabolism in the rat after single and repeated administration of loxapine and haloperidol (European Journal of Pharmacology, 1973)
- Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine (Psychopharmacology, 1975)
- A controlled evaluation of loxitane in seventy-five adolescent schizophrenic patients. (Current Therapeutic Research-clinical and Experimental, 1976)
- Rapid acute treatment of agitation in individuals with schizophrenia: multicentre, randomised, placebo-controlled study of inhaled loxapine (British Journal of Psychiatry, 2011)
- Loxapine in psychogeriatrics: a placebo- and standard-controlled clinical investigation. (Journal of Clinical Psychopharmacology, 1982)
- PET evidence that loxapine is an equipotent blocker of 5-HT2 and D2 receptors: implications for the therapeutics of schizophrenia. (American Journal of Psychiatry, 1997)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Loxapine
- Loxitane
- Loxapine Hydrochloride
- Loxapinsuccinate
- Cloxazepine
- Oxilapine
- Loxipine Succinate
- 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz(b,f)(1,4)oxazepine
- CL 71,563
- CL71,563
- Loxapine Monohydrochloride
- Loxipine Maleate
- CL-71,563
-
SMILESCN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O
-
InChIKeyYQZBAXDVDZTKEQ-UHFFFAOYSA-N
- Pubchem - Loxapine succinate
- Wikipedia - loxapine succinate
Loxapine (several trade names worldwide) is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class and structurally related to clozapine (which belongs to the chemically akin class of dibenzodiazepines). Several researchers have argued that loxapine may behave as an atypical antipsychotic.
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Loxapine succinate
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