Weight | 430.596 g/mol |
---|---|
Formula | C27H34N4O |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 7 |
Piritramide (302-41-0)
Dipydolor · Piritramid · Pirinitramide
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- Sigma-Aldrich - Search for Piritramide
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- Contractile Responses to Morphine, Piritramide, Meperidine, and Fentanyl: A Comparative Study of Effects on the Isolated Ventricular Myocardium (Anesthesiology, 1972)
- Emetic effects of morphine and piritramide (BJA: British Journal of Anaesthesia, 2003)
- A CLINICAL INVESTIGATION OF PIRITRAMIDE IN THE TREATMENT OF POSTOPERATIVE PAIN (BJA: British Journal of Anaesthesia, 1971)
- Clinical evaluation of the new analgesic piritramide. (Acta Anaesthesiologica Scandinavica, 1969)
- Pharmacodynamic modelling of the analgesic effects of piritramide in postoperative patients (Acta Anaesthesiologica Scandinavica, 1997)
- Postoperative pain management and respiratory depression after thoracotomy: A comparison of intramuscular piritramide and intravenous patient-controlled analgesia using fentanyl or buprenorphine (Journal of Clinical Anesthesia, 1991)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dipydolor
- Piritramid
- Pirinitramide
- Dipidolor
- Janssen Brand of Pirinitramide
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SMILESC1CCN(CC1)C2(CCN(CC2)CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)N
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InChIKeyIHEHEFLXQFOQJO-UHFFFAOYSA-N
- Pubchem - Piritramide
- Wikipedia - piritramide
Piritramide (R-3365, trade names Dipidolor, Piridolan, Pirium and others) is a synthetic opioid analgesic (narcotic painkiller) that is marketed in certain European countries including: Austria, Belgium, Czech Republic, Germany and the Netherlands. It comes in free form, is about 0.75x times as potent as morphine and is given parenterally (by injection) for the treatment of severe pain. Nausea, vomiting, respiratory depression and constipation are believed to be less frequent with piritramide than with morphine (the gold standard opioid against which other opioids are compared and contrasted), and it produces more rapid-onset analgesia (pain relief) when compared to morphine and pethidine.
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