| Weight | 340.419 g/mol |
|---|---|
| Formula | C20H17FO2S |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Sulindac sulfide (49627-27-2, 32004-67-4)
sulindac sulfide, sodium salt · sulindac sulfide, (Z)-isomer · sulindac sulfide, (E)-isomer
Score:
#1778 in Biochemistry
,
#3895 in Biology
,
#4906 in Chemistry
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- Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis (Cancer Research, 1995)
- Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells. (Journal of Clinical Investigation, 1995)
- Sulindac Sulfide Is a Noncompetitive -Secretase Inhibitor That Preferentially Reduces A42 Generation (Journal of Biological Chemistry, 2003)
- The anti-proliferative effect of sulindac and sulindac sulfide on HT-29 colon cancer cells: alterations in tumor suppressor and cell cycle-regulatory proteins. (Oncogene, 1996)
- The sulfide metabolite of sulindac prevents tumors and restores enterocyte apoptosis in a murine model of familial adenomatous polyposis (Carcinogenesis, 1998)
- Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29. (Experimental Cell Research, 2001)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - sulindac sulfide, sodium salt
- sulindac sulfide, (Z)-isomer
- sulindac sulfide, (E)-isomer
-
SMILESCC1=C(C2=C(C1=CC3=CC=C(C=C3)SC)C=CC(=C2)F)CC(=O)O
-
InChIKeyLFWHFZJPXXOYNR-UHFFFAOYSA-N
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Sulindac sulfide
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