| Weight | 564.151 g/mol |
|---|---|
| Formula | C22H30ClN3O6S3 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Prochlorperazine edisylate (1257-78-9)
Prochlorperazine · Compazine · Prochlorperazine Maleate
Score:
#172 in Neurology
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#764 in Neuroscience
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#3368 in Biology
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#4193 in Chemistry
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- Antiemetic Efficacy of High-Dose Metoclopramide: Randomized Trials with Placebo and Prochlorperazine in Patients with Chemotherapy-Induced Nausea and Vomiting (The New England Journal of Medicine, 1981)
- Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine. (The New England Journal of Medicine, 1980)
- Randomized, placebo-controlled evaluation of prochlorperazine versus metoclopramide for emergency department treatment of migraine headache (Annals of Emergency Medicine, 1995)
- Superiority of Nabilone over Prochlorperazine as an Antiemetic in Patients Receiving Cancer Chemotherapy (The New England Journal of Medicine, 1979)
- Antiemetic efficacy of dexamethasone. Randomized, double-blind, crossover study with prochlorperazine in patients receiving cancer chemotherapy. (The New England Journal of Medicine, 1984)
- Randomized Double-blind Trial of Intravenous Prochlorperazine for the Treatment of Acute Headache (JAMA, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Prochlorperazine
- Compazine
- Prochlorperazine Maleate
- Prochlorperazine Edisylate Salt
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SMILESCN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl.C(CS(=O)(=O)O)S(=O)(=O)O
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InChIKeySWOUGRBFXFILIB-UHFFFAOYSA-N
- Pubchem - Prochlorperazine edisylate
- Wikipedia - prochlorperazine edisylate
Prochlorperazine is a dopamine (D2) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents that are used for the antiemetic treatment of nausea and vertigo. It is also a highly potent typical antipsychotic, 1020 times more potent than chlorpromazine. It is also used to treat migraine headaches.
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