| Weight | 427.417 g/mol |
|---|---|
| Formula | C20H21N5O6 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 9 |
Pemetrexed (137281-23-3)
Score:
#686 in Biochemistry
,
#1922 in Biology
,
#2330 in Chemistry
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- Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage NonSmall-Cell Lung Cancer (Journal of Clinical Oncology, 2008)
- Randomized Phase III Trial of Pemetrexed Versus Docetaxel in Patients With NonSmall-Cell Lung Cancer Previously Treated With Chemotherapy (Journal of Clinical Oncology, 2004)
- Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma (Journal of Clinical Oncology, 2003)
- Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations (Journal of Clinical Oncology, 2013)
- Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. (The Lancet, 2009)
- The Differential Efficacy of Pemetrexed According to NSCLC Histology: A Review of Two Phase III Studies (Oncologist, 2009)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)O)C(=O)O
-
InChIKeyWBXPDJSOTKVWSJ-UHFFFAOYSA-N
- Pubchem - Pemetrexed
- Wikipedia - pemetrexed
Pemetrexed (brand name Alimta) is a chemotherapy drug manufactured and marketed by Eli Lilly and Company. Its indications are the treatment of pleural mesothelioma and non-small cell lung cancer.
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