| Weight | 208.261 g/mol |
|---|---|
| Formula | C11H16N2O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
pilocarpine (92-13-7, 54-71-7)
Pilocarpine Hydrochloride · Ocusert · Pilocarpine Nitrate
Score:
#405 in Neuroscience
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#1854 in Biology
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#2224 in Chemistry
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- A TEST FOR CONCENTRATION OF ELECTROLYTES IN SWEAT IN CYSTIC FIBROSIS OF THE PANCREAS UTILIZING PILOCARPINE BY IONTOPHORESIS (Pediatrics, 1959)
- Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuropathological study (Behavioural Brain Research, 1983)
- Circuit Mechanisms of Seizures in the Pilocarpine Model of Chronic Epilepsy: Cell Loss and Mossy Fiber Sprouting (Epilepsia, 1993)
- Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. (Epilepsia, 1991)
- Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. (Synapse, 1989)
- The pilocarpine model of temporal lobe epilepsy (Journal of Neuroscience Methods, 2008)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H300: Fatal if swallowed
Danger Acute toxicity, oral - Category 1, 2 - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 - Pilocarpine Hydrochloride
- Ocusert
- Pilocarpine Nitrate
- Salagen
- Isopilocarpine
- Pilocarpine, Monohydrochloride, (3S-cis)-Isomer
- Isoptocarpine
- Pilocarpine Mononitrate, (3S-cis)-Isomer
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SMILESCCC1C(COC1=O)CC2=CN=CN2C
-
InChIKeyQCHFTSOMWOSFHM-UHFFFAOYSA-N
- Pubchem - pilocarpine
- Wikipedia - pilocarpine
Pilocarpine is a medication used to treat increased pressure inside the eye and dry mouth. As eye drops it is used for angle closure glaucoma until surgery can be performed, ocular hypertension, open angle glaucoma, and to bring about constriction of the pupil following their dilation. Onset of effects with the drops is typically within an hour and lasts for up to a day.
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