| Weight | 137.162 g/mol |
|---|---|
| Formula | C7H9N2O+ |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
pralidoxime (6735-59-7)
pralidoxime chloride · Protopam · Protopam Chloride
Score:
#3129 in Biology
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#3912 in Chemistry
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- Pralidoxime Iodide (2-PAM) Penetrates Across the Blood-Brain Barrier (Neurochemical Research, 2003)
- Does pralidoxime affect outcome of management in acute organophosphorus poisoning (The Lancet, 1992)
- Reactivating potency of obidoxime, pralidoxime, HI 6 and HL 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds (Archives of Toxicology, 1998)
- Continuous pralidoxime infusion versus repeated bolus injection to treat organophosphorus pesticide poisoning: a randomised controlled trial. (The Lancet, 2006)
- Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial. (PLOS Medicine, 2009)
- Cholinesterase reactivation in organophosphorus poisoned patients depends on the plasma concentrations of the oxime pralidoxime methylsulphate and of the organophosphate. (Archives of Toxicology, 1993)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - pralidoxime chloride
- Protopam
- Protopam Chloride
- pralidoxime iodide
- pralidoxime mesylate
- pralidoxime trichloroacetate
- pralidoxime methyl sulfate
- Contrathion
- 2-Pam bromide
- 1-methylpyridinium-2-aldoxime ion
- pralidoxime sulfate (1:1)
- pyridine-2-aldoxime methachloride
- 2-hydroxyiminomethyl-1-methylpyridinium
- 2-formyl-1-methylpyridinium chloride oxime
- pyridine-2-aldoxime methochloride
- pralidoxime, 14C-labeled
- 2-hydroxyiminomethylpyridinium methylmethanesulfonate
- pralidoxime lactate (1:1)
- pralidoxime fumarate (1:1)
- pralidoxime nitrate (1:1)
- 2-PAM chloride
- N-methylpyridinium 2-aldoxime methylsulfate
- 2-PAM
- pyridine-2-aldoxime methiodide
- pralidoxime bromide
-
SMILESCN1C=CC=CC1=C[NH+]=O
-
InChIKeyJBKPUQTUERUYQE-UHFFFAOYSA-O
- Pubchem - pralidoxime
- Wikipedia - pralidoxime
Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to combat poisoning by organophosphates or acetylcholinesterase inhibitors (nerve agents) in conjunction with atropine and diazepam. It is a white solid.
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