| Weight | 94.117 g/mol |
|---|---|
| Formula | C5H6N2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 0 |
4-aminopyridine (504-24-5)
VMI103 · Fampridine SR · Fampridine-SR
Score:
#63 in Neuroscience
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#347 in Chemistry
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- Repetitive Action Potentials in Isolated Nerve Terminals in the Presence of 4-Aminopyridine: Effects on Cytosolic Free Ca2+ and Glutamate Release (Journal of Neurochemistry, 1989)
- The effects of 4aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres. (The Journal of Physiology, 1981)
- Physiology and pharmacology of epileptiform activity induced by 4-aminopyridine in rat hippocampal slices (Journal of Neurophysiology, 1991)
- Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres (Nature, 1980)
- 4-Aminopyridine produces epileptiform activity in hippocampus and enhances synaptic excitation and inhibition (Journal of Neurophysiology, 1987)
- A transient outward current in a mammalian central neurone blocked by 4-aminopyridine (Nature, 1982)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H300: Fatal if swallowed
Danger Acute toxicity, oral - Category 1, 2 - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 - H401: Toxic to aquatic life
Hazardous to the aquatic environment, acute hazard - Category 2 - VMI103
- Fampridine SR
- Fampridine-SR
- VMI-103
- Pymadine
- 4 Aminopyridine
- 4-Aminopyridine Sustained Release
- 4 Aminopyridine Sustained Release
- VMI 103
-
SMILESC1=CN=CC=C1N
-
InChIKeyNUKYPUAOHBNCPY-UHFFFAOYSA-N
- Pubchem - 4-aminopyridine
- Wikipedia - dalfampridine
4-Aminopyridine (4-AP, fampridine, dalfampridine) is an organic compound with the chemical formula C5H4NNH2. The molecule is one of the three isomeric amines of pyridine. It is used as a research tool in characterizing subtypes of the potassium channel.
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Estimated Properties
| Boiling Point | 200.44 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.12 g/cm3 | EPA T.E.S.T. |
| Flash Point | 115.12 C | EPA T.E.S.T. |
| Water Solubility | 59799.9 mg/L | EPA T.E.S.T. |
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