propofol (2078-54-8)

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  25 mg
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  100 g
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  25 g
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Most-cited Publications

• Bispectral Analysis Measures Sedation and Memory Effects of Propofol, Midazolam, Isoflurane, and Alfentanil in Healthy Volunteers (Anesthesiology, 1997)
• PHARMACOKINETIC MODEL DRIVEN INFUSION OF PROPOFOL IN CHILDREN (BJA: British Journal of Anaesthesia, 1991)
• The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers. (Anesthesiology, 1998)
• The Influence of Age on Propofol Pharmacodynamics (Anesthesiology, 1999)
• Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil and nitrous oxide anesthesia (Anesthesiology, 1997)
• Propofol. An update on its clinical use. (Anesthesiology, 1994)

Areas of Application

Safety

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  Predict GHS Hazards for Any Chemical in silico.
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Trends

Alternate Names

• Diprivan
• ICI 35,868
• Pisa Brand of Propofol
• Parnell Brand of Propofol
• Curamed Brand of Propofol
• Astra Brand of Propofol
• Propofol Abbott
• ICI35,868
• Propofol Rovi
• Disoprofol
• 2,6-Bis(1-methylethyl)phenol
• 2,6-Diisopropylphenol
• ICI-35868
• ICI 35868
• Rovi Brand of Propofol
• Fresenius Brand of Propofol
• Recofol
• Propofol-Lipuro
• Propofol Fresenius
• Abbott Brand of Propofol
• Aquafol
• ICI-35,868
• Disoprivan
• AstraZeneca Brand of Propofol
• Zeneca Brand of Propofol
• Braun Brand of Propofol
• ICI35868
• Schering Brand of Propofol
• Fresenius Kabi Brand of Propofol
• Ivofol
• Alpha Brand of Propofol
• Propofol MCT
• Fresofol
• 2,6 Diisopropylphenol
• Juste Brand of Propofol
• SMILES
  CC(C)C1=C(C(=CC=C1)C(C)C)O
• InChIKey
  OLBCVFGFOZPWHH-UHFFFAOYSA-N

External Links

• Pubchem - propofol
• Wikipedia - propofol
  Propofol, marketed as Diprivan among others, is a short-acting medication that results in a decreased level of consciousness and lack of memory for events. Its uses include the starting and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. It is also used for status epilepticus if other medications have not worked.

Synthesis

2-Isopropylphenol  +  2-CHLOROPROPANE (Friedel-Crafts alkylation)

Synthesis of propofol ›

Similar Compounds

2,6-DI-TERT-BUTYLPHENOL (128-39-2)

36 alternate names

3 suppliers

2,4-DIISOPROPYLPHENOL (2934-05-6)

36 alternate names

3 suppliers

2-Isopropyl-4-methylphenol (4427-56-9)

36 alternate names

3 suppliers

2,6-Di-tert-butyl-4-methylphenol (25377-21-3, 128-37-0, 950-56-1)

36 alternate names

3 safety hazards

3 suppliers

2,4,6-Tri-tert-butylphenol (732-26-3)

36 alternate names

3 safety hazards

3 suppliers

2,6-Di-tert-butyl-4-ethylphenol (4130-42-1)

36 alternate names

1 safety hazard

3 suppliers

2,6-Diethylphenol (1006-59-3)

36 alternate names

3 suppliers

1879-09-0 (1879-09-0)

36 alternate names

3 safety hazards

3 suppliers

2-Ethyl-6-methylphenol (1687-64-5)

36 alternate names

3 suppliers

2,4-Di-tert-butylphenol (96-76-4)

36 alternate names

4 safety hazards

3 suppliers

2-tert-Butyl-4-methylphenol (2409-55-4)

36 alternate names

2 safety hazards

3 suppliers

2-Isopropylphenol (88-69-7, 25168-06-3)

36 alternate names

3 suppliers

5374-06-1 (5374-06-1)

36 alternate names

3 suppliers

1611-07-0 (1611-07-0)

36 alternate names

3 suppliers

2-Methyl-6-propylphenol (3520-52-3)

36 alternate names

3 suppliers

2-TERT-BUTYLPHENOL (88-18-6, 27178-34-3)

36 alternate names

5 safety hazards

3 suppliers

88-26-6 (88-26-6)

36 alternate names

3 suppliers

3,5-Di-tert-butyl-4-hydroxybenzaldehyde (1620-98-0)

36 alternate names

3 suppliers

3,5-di-tert-butyl-4-hydroxybenzonitrile (1988-88-1)

36 alternate names

3 suppliers

4-Isopropylresorcinol (23504-03-2)

36 alternate names

3 suppliers

4918-95-0 (4918-95-0)

36 alternate names

3 suppliers

3,5-Di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7)

36 alternate names

3 suppliers

2-ETHYLPHENOL (90-00-6, 25429-37-2)

36 alternate names

1 safety hazard

3 suppliers

2,6-DI-TERT-BUTYL-4-METHOXYPHENOL (489-01-0)

36 alternate names

3 suppliers

4-Bromo-2,6-di-tert-butylphenol (1139-52-2)

36 alternate names

3 suppliers

14035-33-7 (14035-33-7)

36 alternate names

3 suppliers

4,4'-METHYLENEBIS(2,6-DI-TERT-BUTYLPHENOL) (118-82-1)

36 alternate names

3 suppliers

3,5-Diethyl-4-hydroxybenzaldehyde (69574-07-8)

36 alternate names

3 suppliers

3,5-Di-tert-butylcatechol (1020-31-1)

36 alternate names

3 suppliers

96-65-1 (96-65-1)

36 alternate names

3 suppliers

20170-32-5 (20170-32-5)

36 alternate names

3 suppliers

6-tert-Butyl-m-cresol (88-60-8)

36 alternate names

5 safety hazards

3 suppliers

6922-60-7 (6922-60-7)

36 alternate names

3 suppliers

88-27-7 (88-27-7)

36 alternate names

3 suppliers

5-Isopropyl-3-methylphenol (3228-03-3)

36 alternate names

3 suppliers

1620-93-5 (1620-93-5)

36 alternate names

3 suppliers

4,6-di-tert-Butylpyrogallol (3934-77-8)

36 alternate names

3 suppliers

2-PROPYLPHENOL (644-35-9, 31019-46-2)

36 alternate names

3 suppliers

3,5-Di-tert-butylphenol (1138-52-9)

36 alternate names

3 suppliers

6386-38-5 (6386-38-5)

36 alternate names

2 safety hazards

3 suppliers

4-tert-butyl-2,6-bis(hydroxymethyl)phenol (2203-14-7)

36 alternate names

3 suppliers

2,4-DINONYLPHENOL (137-99-5)

36 alternate names

3 suppliers

14386-64-2 (14386-64-2)

36 alternate names

3 suppliers

32687-77-7 (32687-77-7)

36 alternate names

3 suppliers

3,5-Di-tert-butyl-4-hydroxybenzoic acid (1421-49-4)

36 alternate names

3 suppliers

2-Ethyl-5-methylphenol (1687-61-2)

36 alternate names

3 suppliers

4-ETHYLRESORCINOL (2896-60-8)

36 alternate names

3 suppliers

2,6-Di-tert-butyl-4-nitrosophenol (955-03-3)

36 alternate names

3 suppliers

119-47-1 (119-47-1)

36 alternate names

3 suppliers

1-(2-hydroxy-3-methylphenyl)ethanone (699-91-2)

36 alternate names

3 suppliers

CARVACROL (499-75-2)

36 alternate names

3 suppliers

3,5-Diisopropyl-4-methoxy-phenylamine (3883-87-2)

36 alternate names

3 suppliers

36294-24-3 (36294-24-3)

36 alternate names

3 suppliers

2-(2-Aminoethyl)phenol (2039-66-9)

36 alternate names

3 suppliers

2725-53-3 (2725-53-3)

36 alternate names

3 suppliers

3-Allyl-2-hydroxybenzaldehyde (24019-66-7)

36 alternate names

3 suppliers

22014-01-3 (22014-01-3)

36 alternate names

3 suppliers

2-Bromo-4,6-di-tert-butylphenol (20834-61-1)

36 alternate names

3 suppliers

55699-10-0 (55699-10-0)

36 alternate names

3 suppliers

3,5-Diisopropylsalicylic acid (2215-21-6)

36 alternate names

3 suppliers

2,6-DIMETHYLPHENOL (25134-01-4, 576-26-1)

36 alternate names

4 safety hazards

3 suppliers

1,3,5-TRIISOPROPYLBENZENE (27322-34-5, 717-74-8)

36 alternate names

3 suppliers

1,3-DIISOPROPYLBENZENE (99-62-7)

36 alternate names

1 safety hazard

3 suppliers

tyrphostin A9 (10537-47-0)

36 alternate names

3 suppliers

Antioxidant 330 (1709-70-2)

36 alternate names

3 suppliers

3-Allyl-4-hydroxybenzaldehyde (41052-88-4)

36 alternate names

3 suppliers

2-tert-Butyl-4-methoxyphenol (121-00-6, 25013-16-5)

36 alternate names

3 suppliers

4-Propylresorcinol (18979-60-7)

36 alternate names

3 suppliers

2-Amino-6-tert-butyl-4-methyl-phenol (19059-89-3)

36 alternate names

3 suppliers

4-Bromo-2-tert-butylphenol (10323-39-4)

36 alternate names

3 suppliers

Thymol methyl ether (1076-56-8)

36 alternate names

3 suppliers

96-66-2 (96-66-2)

36 alternate names

3 suppliers

5325-04-2 (5325-04-2)

36 alternate names

3 suppliers

Antioxidant 245 (36443-68-2)

36 alternate names

3 suppliers

2-(tert-Butyl)-4-chlorophenol (13395-85-2)

36 alternate names

3 suppliers

2-(2-isopropylphenoxy)ethanol (78014-31-0)

36 alternate names

3 suppliers

M-CYMENE (535-77-3)

36 alternate names

3 suppliers

Methyl 3,5-di-tert-butyl-4-hydroxybenzoate (2511-22-0)

36 alternate names

3 suppliers

2-Nonylphenol (84852-15-3, 136-83-4)

36 alternate names

5 safety hazards

3 suppliers

1450-72-2 (1450-72-2)

36 alternate names

3 suppliers

1-(2-bromoethoxy)-2-isopropylbenzene (3245-44-1)

36 alternate names

3 suppliers

Antioxidant 1024 (32687-78-8)

36 alternate names

3 suppliers

2,2'-Ethylidenebis(4,6-di-tert-butylphenol) (35958-30-6)

36 alternate names

3 suppliers

19715-19-6 (19715-19-6)

36 alternate names

2 safety hazards

3 suppliers

4-Isopropylphenol (99-89-8)

36 alternate names

3 suppliers

4'-Hydroxy-3'-methylacetophenone (876-02-8)

36 alternate names

3 suppliers

3-Isopropylphenol (618-45-1, 90480-88-9)

36 alternate names

3 suppliers

2-(2-methoxyphenyl)propan-1-amine (188053-29-4)

36 alternate names

3 suppliers

3'-Allyl-4'-hydroxyacetophenone (1132-05-4)

36 alternate names

3 suppliers

5613-46-7 (5613-46-7)

36 alternate names

3 suppliers

m-Isopropylphenethyl alcohol (68480-22-8)

36 alternate names

3 suppliers

55469-26-6 (55469-26-6)

36 alternate names

3 suppliers

2,4,6-TRIMETHYLPHENOL (527-60-6)

36 alternate names

2 safety hazards

3 suppliers

2082-79-3 (2082-79-3)

36 alternate names

3 suppliers

2,5-Di-tert-amylhydroquinone (79-74-3)

36 alternate names

3 suppliers

4-Cyclohexylresorcinol (2138-20-7)

36 alternate names

3 suppliers

3,5-Di-tert-butyltoluene (15181-11-0)

36 alternate names

3 suppliers

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propofol

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