| Weight | 282.387 g/mol |
|---|---|
| Formula | C18H22N2O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
tyrphostin A9 (10537-47-0)
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- Abnormal localisation and hyperclustering of (alpha)(V)(beta)(3) integrins and associated proteins in Src-deficient or tyrphostin A9-treated osteoclasts. (Journal of Cell Science, 2001)
- Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells. (Journal of Immunology, 1996)
- Tyrphostin A9 and wortmannin perturb the Golgi complex and block proliferation of vascular smooth muscle cells (European Journal of Cell Biology, 1998)
- A receptor tyrosine kinase inhibitor, Tyrphostin A9 induces cancer cell death through Drp1 dependent mitochondria fragmentation. (Biochemical and Biophysical Research Communications, 2011)
- Tyrphostin A9 improves blastocyst development in porcine embryos through induction of dynamin-related protein 1-dependent mitochondrial fission (Mitochondrion, 2017)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N
-
InChIKeyMZOPWQKISXCCTP-UHFFFAOYSA-N
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Alternate Names
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Synthesis
Reactant
+
2-Chloro-2-methylpropane
(Friedel-Crafts alkylation)
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tyrphostin A9
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