| Weight | 184.198 g/mol |
|---|---|
| Formula | C11H8N2O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Tyrphostin 1 (2826-26-8)
3,4-dihydroxybenzylidenemalononitrile · (3,4-dihydroxyphenyl)methylene propanedinitrile · tyrphostin A1
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- The tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD mice. (PLOS ONE, 2012)
- Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition (Biochimica et Biophysica Acta, 2011)
- Novel actions of tyrphostin AG 879: inhibition of RAF-1 and HER-2 expression combined with strong antitumoral effects on breast cancer cells (Cellular and Molecular Life Sciences, 2004)
- Tyrphostin AG490 Agent Modestly but Significantly Prevents Onset of Type 1 in NOD Mouse; Implication of Immunologic and Metabolic Effects of a Jak-Stat Pathway Inhibitor (Journal of Clinical Immunology, 2012)
- Inhibitory effect of tyrphostin on the replication of herpes simplex virus type 1. (Archives of Virology, 1995)
- Tyrosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells (Cancer Letters, 2015)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 3,4-dihydroxybenzylidenemalononitrile
- (3,4-dihydroxyphenyl)methylene propanedinitrile
- tyrphostin A1
- RG-50810
- RG 50810
- tyrphostin A23
- tyrphostin 23
- tyrphostin AG18
- tyrphostin RG50810
- (3,4-dihydroxybenzylidene)malononitrile
-
SMILESCOC1=CC=C(C=C1)C=C(C#N)C#N
-
InChIKeyUOHFCPXBKJPCAD-UHFFFAOYSA-N
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Tyrphostin 1
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