| Weight | 219.332 g/mol |
|---|---|
| Formula | C13H21N3 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
QUINPIROLE (74196-92-2, 80373-22-4)
Score:
#1189 in Neuroscience
,
#5119 in Biology
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- Dopamine D-1 receptor agonists combined with the selective D-2 agonist quinpirole facilitate the expression of oral stereotyped behaviour in rats (European Journal of Pharmacology, 1987)
- Quinpirole Induces Compulsive Checking Behavior in Rats: A Potential Animal Model of Obsessive-Compulsive Disorder (OCD) (Behavioral Neuroscience, 1998)
- Dopamine D2 receptor mechanisms contribute to age-related cognitive decline: the effects of quinpirole on memory and motor performance in monkeys (The Journal of Neuroscience, 1995)
- Biphasic effect of D-2 agonist quinpirole on locomotion and movements (European Journal of Pharmacology, 1989)
- Continuous treatment with the D2 dopamine receptor agonist quinpirole decreases D2 dopamine receptors, D2 dopamine receptor messenger RNA and proenkephalin messenger RNA, and increases mu opioid receptors in mouse striatum (Neuroscience, 1993)
- The Selective mGlu5 Receptor Agonist CHPG Inhibits Quinpirole-Induced Turning in 6-Hydroxydopamine-Lesioned Rats and Modulates the Binding Characteristics of Dopamine D2 Receptors in the Rat Striatum : Interactions with Adenosine A2a Receptors (Neuropsychopharmacology, 2001)
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SMILESCCCN1CCCC2C1CC3=C(C2)NN=C3
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InChIKeyFTSUPYGMFAPCFZ-UHFFFAOYSA-N
- Pubchem - QUINPIROLE
- Wikipedia - quinpirole
Quinpirole is a psychoactive drug and research chemical which acts as a selective D2 and D3 receptor agonist. It is used in scientific research. Quinpirole has been shown to increase locomotion and sniffing behavior in mice treated with it.
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