| Weight | 914.187 g/mol |
|---|---|
| Formula | C51H79NO13 |
| Hydrogen Acceptors | 13 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 6 |
Rapamycin (53123-88-9)
Score:
#9 in Molecular and cellular biology
,
#325 in Biochemistry
,
#1209 in Biology
,
#1385 in Chemistry
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- Rapamycin fed late in life extends lifespan in genetically heterogeneous mice (Nature, 2009)
- Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB (Molecular Cell, 2006)
- Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. (Current Biology, 2004)
- Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor (Nature Medicine, 2002)
- A mammalian protein targeted by G1-arresting rapamycin-receptor complex (Nature, 1994)
- Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive (Nature Cell Biology, 2004)
-
SMILESCC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
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InChIKeyQFJCIRLUMZQUOT-UHFFFAOYSA-N
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