| Weight | 788.881 g/mol |
|---|---|
| Formula | C35H48N8O11S |
| Hydrogen Acceptors | 12 |
| Hydrogen Donors | 11 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Phalloidine (17466-45-4)
Phalloidin
Score:
#43 in Molecular and cellular biology
,
#1387 in Biochemistry
,
#3333 in Biology
,
#4155 in Chemistry
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- Effects of cytochalasin and phalloidin on actin. (Journal of Cell Biology, 1987)
- Jasplakinolide, a Cytotoxic Natural Product, Induces Actin Polymerization and Competitively Inhibits the Binding of Phalloidin to F-actin* (Journal of Biological Chemistry, 1994)
- Flexibility of actin filaments derived from thermal fluctuations. Effect of bound nucleotide, phalloidin, and muscle regulatory proteins (Journal of Biological Chemistry, 1995)
- Effects of cytochalasin, phalloidin and pH on the elongation of actin filaments (Biochemistry, 1991)
- Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidin-binding site. (Molecular Biology of the Cell, 1993)
- Interaction of actin with phalloidin:: Polymerization and stabilization of F-actin (Biochimica et Biophysica Acta, 1975)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Phalloidin
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SMILESCC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C)C(C)O
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InChIKeyKPKZJLCSROULON-UHFFFAOYSA-N
- Pubchem - Phalloidine
- Wikipedia - phalloidin
Phalloidin belongs to a class of toxins called phallotoxins, which are found in the death cap mushroom (Amanita phalloides). It is a rigid bicyclic heptapeptide that is lethal after a few days when injected into the bloodstream. The major symptom of phalloidin poisoning is acute hunger due to the destruction of liver cells.
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