| Weight | 685.7 g/mol |
|---|---|
| Formula | C25H43N13O10 |
| Hydrogen Acceptors | 15 |
| Hydrogen Donors | 15 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 10 |
VIOMYCIN (32988-50-4, 37883-00-4)
Viocin · Vinactane · Viomicin
Score:
#508 in Microbiology
,
#1881 in Biochemistry
,
#4036 in Biology
,
#5088 in Chemistry
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- Molecular Analysis of Cross-Resistance to Capreomycin, Kanamycin, Amikacin, and Viomycin in Mycobacterium tuberculosis (Antimicrobial Agents and Chemotherapy, 2005)
- The antibiotic viomycin traps the ribosome in an intermediate state of translocation (Nature Structural & Molecular Biology, 2007)
- The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome (Nature Structural & Molecular Biology, 2010)
- The Inhibition of Ribosomal Translocation by Viomycin (FEBS Journal, 1977)
- The Allosteric Three-site Model for the Ribosomal Elongation Cycle NEW INSIGHTS INTO THE INHIBITION MECHANISMS OF AMINOGLYCOSIDES, THIOSTREPTON, AND VIOMYCIN* (Journal of Biological Chemistry, 1988)
- Molecular analysis of kanamycin and viomycin resistance in Mycobacterium smegmatis by use of the conjugation system. (Journal of Bacteriology, 1997)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Viocin
- Vinactane
- Viomicin
- Celiomycin
- Florimycin
- Tuberactinomycin B
- Viomycins
-
SMILESC1C(NC(=NC1O)N)C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)N2)CO)CO)NC(=O)CC(CCCN)N
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- Pubchem - VIOMYCIN
- Wikipedia - viomycin sulfate
Viomycin is a member of the tuberactinomycin family, a group of nonribosomal peptide antibiotics exhibiting anti-tuberculosis properties. The tuberactinomycin family is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis. Viomycin was the first member of the tuberactinomycins to be isolated and identified and was used to treat TB until it was replaced by the less toxic, but structurally related compound, capreomycin.
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