| Weight | 831.979 g/mol |
|---|---|
| Formula | C35H49N11O9S2 |
| Hydrogen Acceptors | 11 |
| Hydrogen Donors | 10 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 10 |
Eptifibatide (188627-80-7)
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- Early versus Delayed, Provisional Eptifibatide in Acute Coronary Syndromes (The New England Journal of Medicine, 2009)
- Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets. Results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) Study (Circulation, 2005)
- Platelet Glycoprotein IIb/IIIa Integrin Blockade With Eptifibatide in Coronary Stent Intervention: The ESPRIT Trial: A Randomized Controlled Trial (JAMA, 2001)
- Clinical pharmacology of eptifibatide (American Journal of Cardiology, 1997)
- Randomized Evaluation of the Safety and Efficacy of Enoxaparin Versus Unfractionated Heparin in High-Risk Patients With Non-ST-Segment Elevation Acute Coronary Syndromes Receiving the Glycoprotein IIb/IIIa Inhibitor Eptifibatide (Circulation, 2003)
- Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa (Blood, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
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- Pubchem - Eptifibatide
- Wikipedia - eptifibatide
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the arginin-glycin-aspartat-mimetics and reversibly binds to platelets.
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