| Weight | 471.521 g/mol |
|---|---|
| Formula | C25H25N7O3 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 9 |
Dabigatran (211914-51-1)
Score:
#71 in Neurology
,
#355 in Neuroscience
,
#1615 in Biology
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#1903 in Chemistry
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- Dabigatran versus Warfarin in Patients with Atrial Fibrillation (The New England Journal of Medicine, 2009)
- Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism (The New England Journal of Medicine, 2009)
- Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity (Thrombosis and Haemostasis, 2010)
- Reversal of Rivaroxaban and Dabigatran by Prothrombin Complex Concentrate A Randomized, Placebo-Controlled, Crossover Study in Healthy Subjects (Circulation, 2011)
- Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial (The Lancet, 2007)
- Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial (Journal of Thrombosis and Haemostasis, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
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InChIKeyYBSJFWOBGCMAKL-UHFFFAOYSA-N
- Pubchem - Dabigatran
- Wikipedia - dabigatran
Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant medication which can be taken by mouth. It is used as an alternative to warfarin, since it does not have to be monitored by blood tests, but offers similar results in terms of efficacy. It is a direct thrombin inhibitor, and functions by directly inhibiting both free and fibrin-bound thrombin.
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Dabigatran
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