| Weight | 670.855 g/mol |
|---|---|
| Formula | C38H50N6O5 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 12 |
SAQUINAVIR (127779-20-8)
Score:
#90 in Microbiology
,
#269 in Biochemistry
,
#1050 in Biology
,
#1171 in Chemistry
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- Treatment of Human Immunodeficiency Virus Infection with Saquinavir, Zidovudine, and Zalcitabine (The New England Journal of Medicine, 1996)
- The Effect of Garlic Supplements on the Pharmacokinetics of Saquinavir (Clinical Infectious Diseases, 2002)
- Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir. (British Journal of Clinical Pharmacology, 2003)
- The Effect of High-Dose Saquinavir on Viral Load and CD4+ T-Cell Counts in HIV-Infected Patients (Annals of Internal Medicine, 1996)
- Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients. (AIDS, 1997)
- Atazanavir plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures. (AIDS, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(C(CC3=CC=CC=C3)NC(=O)C(CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O
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InChIKeyQWAXKHKRTORLEM-UHFFFAOYSA-N
- Pubchem - SAQUINAVIR
- Wikipedia - saquinavir
Saquinavir, sold under the brand names Invirase and Fortovase, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. Typically it is used with ritonavir or lopinavir/ritonavir to increase its effect. It is taken by mouth.
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