| Weight | 547.073 g/mol |
|---|---|
| Formula | C27H31ClN2O6S |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 9 |
Bepotastine besilate (190786-44-8)
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- Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate (Drug Metabolism and Disposition, 2006)
- Time to onset and duration of action of the antihistamine bepotastine besilate ophthalmic solutions 1.0% and 1.5% in allergic conjunctivitis: A phase III, single-center, prospective, randomized, double-masked, placebo-controlled, conjunctival allergen challenge assessment in adults and children (Clinical Therapeutics, 2009)
- Suppression by bepotastine besilate of substance P-induced itch-associated responses through the inhibition of the leukotriene B4 action in mice (European Journal of Pharmacology, 2006)
- Bepotastine besilate, a highly selective histamine H1 receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models (Experimental Eye Research, 2010)
- Bepotastine besilate OD tablets suppress nasal symptoms caused by Japanese cedar pollen exposure in an artificial exposure chamber (OHIO Chamber) (Expert Opinion on Pharmacotherapy, 2009)
- Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate (Current Medical Research and Opinion, 2010)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CN(CCC1OC(C2=CC=C(C=C2)Cl)C3=CC=CC=N3)CCCC(=O)O.C1=CC=C(C=C1)S(=O)(=O)O
-
InChIKeyUDGHXQPQKQPSBB-UHFFFAOYSA-N
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