Weight | 437.477 g/mol |
---|---|
Formula | C21H32N3O5P |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 4 |
Aromatic Rings | 2 |
Rotatable Bonds | 8 |
DISOPYRAMIDE PHOSPHATE (22059-60-5)
Disopyramide · Norpace · Ritmilen
Score:
#3590 in Biology
,
#4505 in Chemistry
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- The pharmacokinetics of Norpace. (Angiology, 1975)
- New antiarrhythmic agents: amiodarone, aprindine, disopyramide, ethmozin, mexiletine, tocainide, verapamil. (American Journal of Cardiology, 1978)
- Congestive Heart Failure Caused by Oral Disopyramide (The New England Journal of Medicine, 1980)
- Multicenter study of the efficacy and safety of disopyramide in obstructive hypertrophic cardiomyopathy (Journal of the American College of Cardiology, 2005)
- Muscular subaortic stenosis: hemodynamic and clinical improvement after disopyramide. (The New England Journal of Medicine, 1982)
- A placebo-controlled trial of intravenous and oral disopyramide for prevention of neurally mediated syncope induced by heap-up tilt (Journal of the American College of Cardiology, 1993)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Disopyramide
- Norpace
- Ritmilen
- Disopyramide Phosphate (1:1), (R)-Isomer
- Disopyramide, (+-)-Isomer
- Disopyramide, (S)-Isomer
- Disopyramide Phosphate (1:1), (S)-Isomer
- Disopyramide, L-Tartrate, (S)-isomer
- SC-13957
- Palpitine
- Disopyramide, L-Tartrate (1:1), (S)-Isomer
- Diisopyramide
- SC13957
- Disopyramide, L-Tartrate (1:1), (R)-Isomer
- Disopyramide, L-Tartrate (1:2), (+-)-Isomer
- SC 13957
- Disopyramide Monohydrochloride
- Disopyramide, (R)-Isomer
- Palpitin
- Rythmilen
- Disopyramide Phosphate (1:1), (+-)-Isomer
- Disopyramide Phosphate (1:1)
- Disopyramide, D-Tartrate (1:1), (S)-Isomer
- Rhythmodan
- Searle Brand of Disopyramide Phosphate
-
SMILESCC(C)N(CCC(C1=CC=CC=C1)(C2=CC=CC=N2)C(=O)N)C(C)C.OP(=O)(O)O
-
InChIKeyCGDDQFMPGMYYQP-UHFFFAOYSA-N
- Pubchem - DISOPYRAMIDE PHOSPHATE
- Wikipedia - disopyramide phosphate
Disopyramide (INN, trade names Norpace and Rythmodan) is an antiarrhythmic medication used in the treatment of ventricular tachycardia. It is a sodium channel blocker and therefore classified as a Class 1a anti-arrhythmic agent. Disopyramide has a negative inotropic effect on the ventricular myocardium, significantly decreasing the contractility.
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