| Weight | 300.442 g/mol |
|---|---|
| Formula | C20H28O2 |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 5 |
Retinoic acid
Tretinoin · Vitamin A Acid · trans Retinoic Acid
302-79-4, 4759-48-2, 97950-17-9
Score:
#98 in Biochemistry
,
#431 in Biology
,
#447 in Chemistry
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- Sigma-Aldrich - Retinoic acid34.30 - 755.00 USD
- Fisher Scientific - Search for Retinoic acid
- TCI - Search for Retinoic acid
- A decade of molecular biology of retinoic acid receptors. (The FASEB Journal, 1996)
- A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. (Journal of Experimental Medicine, 2007)
- Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia (Blood, 1988)
- A human retinoic acid receptor which belongs to the family of nuclear receptors. (Nature, 1987)
- Identification of a receptor for the morphogen retinoic acid. (Nature, 1987)
- Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. (Proceedings of the National Academy of Sciences of the United States of America, 1980)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Tretinoin
- Vitamin A Acid
- trans Retinoic Acid
- Retin A
- Vesanoid
- all trans Retinoic Acid
- trans-Retinoic Acid
- beta all trans Retinoic Acid
- Retin-A
- Tretinoin Potassium Salt
- beta-all-trans-Retinoic Acid
- all-trans-Retinoic Acid
- Tretinoin Sodium Salt
- Tretinoin Zinc Salt
-
SMILESCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
-
InChIKeySHGAZHPCJJPHSC-UHFFFAOYSA-N
- Pubchem - Retinoic acid
- Wikipedia - isotretinoin
Isotretinoin, also known as 13-cis-retinoic acid (and colloquially referred to by its former brand name Accutane), is a medication primarily used to treat severe acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis.
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Synthesis
2-ethenyl-1,3,3-trimethylcyclohexene
+
Reactant
(Heck terminal vinyl)
1,3,3-Trimethylcyclohexene
+
Reactant
(Heck non-terminal vinyl)
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Retinoic acid
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