| Weight | 386.561 g/mol |
|---|---|
| Formula | C22H30N2O2S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 8 |
SUFENTANIL (56030-54-7)
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#351 in Neuroscience
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#1604 in Biology
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#1888 in Chemistry
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- Halothane-morphine compared with high-dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery (The New England Journal of Medicine, 1992)
- Electroencephalographic quantitation of opioid effect: comparative pharmacodynamics of fentanyl and sufentanil. (Anesthesiology, 1991)
- Comparative spinal distribution and clearance kinetics of intrathecally administered morphine, fentanyl, alfentanil, and sufentanil. (Anesthesiology, 2000)
- Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein. (Anesthesiology, 2002)
- The Pharmacokinetics of Sufentanil in Surgical Patients (Anesthesiology, 1984)
- Safety of sedation with ketamine in severe head injury patients: Comparison with sufentanil (Critical Care Medicine, 2003)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CS3)COC
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InChIKeyGGCSSNBKKAUURC-UHFFFAOYSA-N
- Pubchem - SUFENTANIL
- Wikipedia - sufentanil
Sufentanil (R30730, brand name Sufenta) is a synthetic opioid analgesic drug approximately 5 to 10 times more potent than its parent drug, fentanyl, and 500 times as potent as morphine. Structurally, sufentanil differs from fentanyl through the addition of a methoxymethyl group on the piperidine ring (which is believed to reduce duration of action), and the replacement of the phenyl ring by thiophene. Sufentanil first was synthesized at Janssen Pharmaceutica in 1974.
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