| Weight | 340.471 g/mol |
|---|---|
| Formula | C20H28N4O |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
terguride (37686-84-3)
transdihydrolisuride · VUFB 6638 · dironyl maleate (1:1)
Score:
#210 in Neurology
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#945 in Neuroscience
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#4141 in Biology
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#5223 in Chemistry
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- Dual action on central dopamine function of transdihydrolisuride, a 9, 10-dihydrogenated analogue of the ergot dopamine agonist lisuride (Life Sciences, 1983)
- Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats (European Respiratory Journal, 2011)
- Transdihydrolisuride, a partial dopamine receptor antagonist: effects on monoamine metabolism (European Journal of Pharmacology, 1984)
- Characterization of the Effects of the Partial Dopamine Agonist Terguride on Cocaine Self-Administration in the Rat (Journal of Pharmacology and Experimental Therapeutics, 1998)
- Effects of the partial dopamine receptor agonists SDZ 208-911, SDZ 208-912 and terguride on central monoamine receptors. A behavioral, biochemical and electrophysiological study. (Naunyn-schmiedebergs Archives of Pharmacology, 1991)
- The effect of the partial dopamine agonist terguride on negative symptoms in schizophrenics. (Pharmacopsychiatry, 1988)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - transdihydrolisuride
- VUFB 6638
- dironyl maleate (1:1)
- N-(D-6-methyl-8-isoergolin-1-yl)-N',N'-diethylurea
- dironyl
-
SMILESCCN(CC)C(=O)NC1CC2C(CC3=CNC4=CC=CC2=C34)N(C1)C
-
InChIKeyJOAHPSVPXZTVEP-UHFFFAOYSA-N
- Pubchem - terguride
- Wikipedia - terguride
Terguride (INN), also known as trans-dihydrolisuride, is a serotonin receptor antagonist and dopamine receptor agonist of the ergoline family. It is approved for and used as a prolactin inhibitor in the treatment of hyperprolactinemia. Terguride is an oral, potent antagonist of 5-HT2B and 5-HT2A (serotonin) receptors.
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