| Weight | 408.472 g/mol |
|---|---|
| Formula | C20H24O7S |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 11 |
Tesaglitazar (251565-85-2)
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- Sigma-Aldrich - Tesaglitazar86.30 - 338.50 USD
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- Tesaglitazar, a novel dual peroxisome proliferator-activated receptor / agonist, dose-dependently improves the metabolic abnormalities associated with insulin resistance in a non-diabetic population (Diabetologia, 2005)
- Peroxisome Proliferator-Activated Receptor (PPAR) Activation Induces Tissue-Specific Effects on Fatty Acid Uptake and Metabolism in VivoA Study Using the Novel PPAR/ Agonist Tesaglitazar (Endocrinology, 2004)
- Peroxisome ProliferatorActivated Receptor / Dual Agonist Tesaglitazar Attenuates Diabetic Nephropathy in db/db Mice (Diabetes, 2007)
- Models for Plasma Glucose, HbA1c, and Hemoglobin Interrelationships in Patients with Type 2 Diabetes Following Tesaglitazar Treatment (Clinical Pharmacology & Therapeutics, 2008)
- Effect of tesaglitazar, a dual PPAR/ agonist, on glucose and lipid abnormalities in patients with type 2 diabetes: a 12week dose-ranging trial (Current Medical Research and Opinion, 2006)
- Efficacy, safety and tolerability of tesaglitazar when added to the therapeutic regimen of poorly controlled insulin-treated patients with type 2 diabetes (Diabetes and Vascular Disease Research, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
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- Pubchem - Tesaglitazar
- Wikipedia - tesaglitazar
Tesaglitazar (also known as AZ 242) is a dual peroxisome proliferator-activated receptor agonist with affinity to PPAR and PPAR, proposed for the management of type 2 diabetes. The drug had completed several phase III clinical trials, however in May, 2006 AstraZeneca announced that it had discontinued further development.
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Tesaglitazar
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