| Weight | 288.497 g/mol |
|---|---|
| Formula | C16H32O2S |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 15 |
Tetradecylthioacetic acid (2921-20-2)
Score:
#2808 in Biochemistry
,
#5259 in Biology
,
#6910 in Chemistry
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- Modulation of Keratinocyte Gene Expression and Differentiation by PPAR-Selective Ligands and Tetradecylthioacetic Acid (Journal of Investigative Dermatology, 2001)
- MODULATION OF RAT LIVER APOLIPOPROTEIN GENE EXPRESSION AND SERUM LIPID LEVELS BY TETRADECYLTHIOACETIC ACID (TTA) VIA PPARALPHA ACTIVATION (Journal of Lipid Research, 1999)
- Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways (Carcinogenesis, 2001)
- Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance (Journal of Lipid Research, 2002)
- Fatty Acid Incubation of Myotubes From Humans With Type 2 Diabetes Leads to Enhanced Release of -Oxidation Products Because of Impaired Fatty Acid Oxidation: Effects of Tetradecylthioacetic Acid and Eicosapentaenoic Acid (Diabetes, 2009)
- Up-regulated delta 9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: accumulation of a delta 9-desaturated metabolite of tetradecylthioacetic acid. (Journal of Lipid Research, 1997)
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SMILESCCCCCCCCCCCCCCSCC(=O)O
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InChIKeyIPBCWPPBAWQYOO-UHFFFAOYSA-N
- Pubchem - Tetradecylthioacetic acid
- Wikipedia - tetradecylthioacetic acid
Tetradecylthioacetic acid (TTA) is a synthetic fatty acid used as a nutritional supplement. TTA acts as a peroxisome proliferator-activated receptor alpha (PPAR) agonist and increases mitochondrial fatty acid oxidation in vitro. In rodent studies, TTA has been reported to have other activities such as reducing inflammation and preventing high fat diet induced adiposity and insulin resistance.
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Tetradecylthioacetic acid
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